Bupivacaine Hydrochloride Injection shortage
Current 62 presentations · 8 manufacturers · first FDA posting Feb 20, 2018 · last update Oct 15, 2026
Manufacturers: Aspiro Pharma Limited, Eugia US LLC, Fresenius Kabi USA, LLC, Hospira, Inc., a Pfizer Company, Huons Co., Ltd, Kindos Pharmaceuticals Co. Ltd., ONESOURCE SPECIALTY PTE LTD, Somerset Therapeutics, LLC
Stated reasons (per FDA): Delay in shipping of the drug; Demand increase for the drug; Discontinuation of the manufacture of the drug; Other
More info: FDA Drug Shortages Database · ASHP drug shortages list (search there for this drug)
Presentations
| Presentation | Manufacturer | Status | Reason | Notes (FDA) | Dates |
|---|---|---|---|---|---|
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 31722-275-32) | Aspiro Pharma Limited | Current Available |
— | Posted Feb 20, 2018 Updated Jul 17, 2026 | |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 31722-275-34) | Aspiro Pharma Limited | Current Available |
— | Posted Feb 20, 2018 Updated Jul 17, 2026 | |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 31722-276-32) | Aspiro Pharma Limited | Current Available |
— | Posted Feb 20, 2018 Updated Jul 17, 2026 | |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 31722-276-34) | Aspiro Pharma Limited | Current Available |
— | Posted Feb 20, 2018 Updated Jul 17, 2026 | |
| Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 31722-277-32) | Aspiro Pharma Limited | Current Available |
— | Posted Feb 20, 2018 Updated Jul 17, 2026 | |
| Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 31722-277-34) | Aspiro Pharma Limited | Current Available |
— | Posted Feb 20, 2018 Updated Jul 17, 2026 | |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-167-10) | Eugia US LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 2, 2026 |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-168-30) | Eugia US LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 2, 2026 |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-169-10) | Eugia US LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 2, 2026 |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-170-30) | Eugia US LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 2, 2026 |
| Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 55150-171-10) | Eugia US LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 2, 2026 |
| Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 55150-172-30) | Eugia US LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 2, 2026 |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-249-50) | Eugia US LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 2, 2026 |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-250-50) | Eugia US LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 2, 2026 |
| Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-17) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 15, 2026 |
| Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-31) | Fresenius Kabi USA, LLC | Current Unavailable |
Demand increase for the drug | Estimated recovery: TBD | Posted Feb 20, 2018 Updated Oct 15, 2026 |
| Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-37) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 15, 2026 |
| Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-465-57) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 15, 2026 |
| Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-17) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 15, 2026 |
| Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-31) | Fresenius Kabi USA, LLC | Current Unavailable |
Delay in shipping of the drug | Estimated recovery: TBD | Posted Feb 20, 2018 Updated Oct 15, 2026 |
| Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-37) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 15, 2026 |
| Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-467-57) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 15, 2026 |
| Sensorcaine, Injection, 7.5 mg/1 mL (NDC 63323-472-17) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 15, 2026 |
| Sensorcaine, Injection, 7.5 mg/1 mL (NDC 63323-472-37) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted Feb 20, 2018 Updated Oct 15, 2026 |
| Marcaine, Injection, 250 mg/50 mL (NDC 0409-0525-25) | Hospira, Inc., a Pfizer Company | Current Available |
— | Historical NDC: 0409-1610-50 | Posted Feb 20, 2018 Updated Oct 8, 2026 |
| Bupivacaine Hydrochloride, Injection, 25 mg/10 mL (2.5 mg/mL) (NDC 0409-1159-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Bupivacaine Hydrochloride, Injection, 75 mg/30 mL (2.5 mg/mL) (NDC 0409-1159-02) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Bupivacaine Hydrochloride, Injection, 125 mg/50 mL (2.5 mg/mL) (NDC 0409-1160-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Marcaine, Injection, Marcaine 125 mg/50 mL (2.5 mg/mL) (NDC 0409-1160-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Bupivacaine Hydrochloride, Injection, 50 mg/10 mL (5 mg/mL) (NDC 0409-1162-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Bupivacaine Hydrochloride, Injection, 150 mg/30 mL (5 mg/mL) (NDC 0409-1162-02) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Bupivacaine Hydrochloride, Injection, 250 mg/50 mL (5 mg/mL) (NDC 0409-1163-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 0409-1165-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Marcaine, Injection, Marcaine 75 mg/10 mL (7.5 mg/mL) (NDC 0409-1165-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Bupivacaine Hydrochloride, Injection, 225 mg/30 mL (7.5 mg/mL) (NDC 0409-1165-02) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Marcaine, Injection, 150 mg/30 mL (5 mg/mL) (NDC 0409-1530-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Marcaine, Injection, 0.75% 15 mg/2 mL (7.5 mg/mL) in Dextrose 8.25% (NDC 0409-1761-10) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery: November 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay | Posted Feb 20, 2018 Updated Oct 8, 2026 |
| Marcaine, Injection, 0.75% 15 mg/2 mL (NDC 0409-1761-62) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Marcaine, Injection, Marcaine 225 mg/30 mL (7.5 mg/mL) (NDC 0409-2253-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Historical NDC: 0409-1582-29 | Posted Feb 20, 2018 Updated Oct 8, 2026 |
| Marcaine, Injection, 225 mg/30 mL (NDC 0409-2253-25) | Hospira, Inc., a Pfizer Company | Current Available |
— | Historical NDC: 0409-1582-29 | Posted Feb 20, 2018 Updated Oct 8, 2026 |
| Marcaine, Injection, 25 mg/10 mL (2.5 mg/mL) (NDC 0409-2510-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Bupivacaine Hydrochloride, Injection, Bupivacaine Spinal 15 mg/2 mL (7.5 mg/mL in 8.25% dextrose) (NDC 0409-3613-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Marcaine, Injection, 50 mg/10 mL (5 mg/mL) (NDC 0409-5010-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Marcaine, Injection, 75 mg/30 mL (2.5 mg/mL) (NDC 0409-7535-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Feb 20, 2018 Updated Oct 8, 2026 | |
| Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 73293-0002-2) | Huons Co., Ltd | Current Unavailable |
Demand increase for the drug | Estimated recovery: TBD | Posted Feb 20, 2018 Updated Jul 30, 2026 |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-722-32) | Kindos Pharmaceuticals Co. Ltd. | Current Limited Availability |
Discontinuation of the manufacture of the drug | Meitheal Pharmaceuticals is distributor/labeler | Posted Feb 20, 2018 Updated May 5, 2026 |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-723-52) | Kindos Pharmaceuticals Co. Ltd. | Current Limited Availability |
Discontinuation of the manufacture of the drug | Meitheal Pharmaceuticals is distributor/labeler | Posted Feb 20, 2018 Updated May 5, 2026 |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 71288-725-32) | Kindos Pharmaceuticals Co. Ltd. | Current Limited Availability |
Discontinuation of the manufacture of the drug | Meitheal Pharmaceuticals is distributor/labeler | Posted Feb 20, 2018 Updated May 5, 2026 |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 71288-726-52) | Kindos Pharmaceuticals Co. Ltd. | Current Limited Availability |
Discontinuation of the manufacture of the drug | Meitheal Pharmaceuticals is distributor/labeler | Posted Feb 20, 2018 Updated May 5, 2026 |
| Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 71288-728-32) | Kindos Pharmaceuticals Co. Ltd. | Current Limited Availability |
Discontinuation of the manufacture of the drug | Meitheal Pharmaceuticals is distributor/labeler | Posted Feb 20, 2018 Updated May 5, 2026 |
| Bupivacaine Hydrochloride PRESERVATIVE FREE, Injection, 2.5 mg/1 mL 5mg / 1mL (NDC 72266-263-10) | ONESOURCE SPECIALTY PTE LTD | Current Available |
— | Distributed by Fosun Pharma USA Inc. | Posted Feb 20, 2018 Updated Sep 18, 2026 |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-01) | Somerset Therapeutics, LLC | Current Available |
— | Posted Feb 20, 2018 Updated Sep 11, 2026 | |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-10) | Somerset Therapeutics, LLC | Current Available |
— | Posted Feb 20, 2018 Updated Sep 11, 2026 | |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-25) | Somerset Therapeutics, LLC | Current Available |
— | Posted Feb 20, 2018 Updated Sep 11, 2026 | |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 70069-753-01) | Somerset Therapeutics, LLC | Current Available |
— | Posted Feb 20, 2018 Updated Sep 11, 2026 | |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 70069-753-10) | Somerset Therapeutics, LLC | Current Available |
— | Posted Feb 20, 2018 Updated Sep 11, 2026 | |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 70069-753-25) | Somerset Therapeutics, LLC | Current Available |
— | Posted Feb 20, 2018 Updated Sep 11, 2026 | |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-722-32) | Kindos Pharmaceuticals Co. Ltd. | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted May 5, 2026 Updated May 5, 2026 Discontinued May 5, 2026 |
| Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-723-52) | Kindos Pharmaceuticals Co. Ltd. | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted May 5, 2026 Updated May 5, 2026 Discontinued May 5, 2026 |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 71288-725-32) | Kindos Pharmaceuticals Co. Ltd. | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted May 5, 2026 Updated May 5, 2026 Discontinued May 5, 2026 |
| Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 71288-726-52) | Kindos Pharmaceuticals Co. Ltd. | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted May 5, 2026 Updated May 5, 2026 Discontinued May 5, 2026 |
| Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 71288-728-32) | Kindos Pharmaceuticals Co. Ltd. | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted May 5, 2026 Updated May 5, 2026 Discontinued May 5, 2026 |