Promethazine Hydrochloride Injection shortage
Current 10 presentations · 2 manufacturers · first FDA posting Nov 21, 2023 · last update Oct 14, 2026
Manufacturers: Hikma Pharmaceuticals USA, Inc., XGen Pharmaceuticals DJB, Inc.
Stated reasons (per FDA): Demand increase for the drug; Other
More info: FDA Drug Shortages Database · ASHP drug shortages list (search there for this drug)
Presentations
| Presentation | Manufacturer | Status | Reason | Notes (FDA) | Dates |
|---|---|---|---|---|---|
| Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-0928-25) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
Demand increase for the drug | Additional lots will be available in the October 2026 timeframe. Product will be made available as it is released. | Posted Nov 21, 2023 Updated Sep 18, 2026 |
| Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-0929-25) | Hikma Pharmaceuticals USA, Inc. | Current Limited Availability |
Demand increase for the drug | Estimated recovery: TBD | Posted Nov 21, 2023 Updated Sep 18, 2026 |
| Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-1495-35) | Hikma Pharmaceuticals USA, Inc. | Current Available |
Demand increase for the drug | Limited availability | Posted Nov 21, 2023 Updated Sep 18, 2026 |
| Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-1496-35) | Hikma Pharmaceuticals USA, Inc. | Current Available |
— | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted Nov 21, 2023 Updated Oct 14, 2026 |
| Phenergan, Injection, 25 mg/1 mL (NDC 0641-6082-25) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
Other | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted Nov 21, 2023 Updated Sep 18, 2026 |
| Phenergan, Injection, 50 mg/1 mL (NDC 0641-6083-25) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
— | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted Nov 21, 2023 Updated Sep 18, 2026 |
| Phenergan, Injection, 25 mg/1 mL (NDC 0641-6084-25) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
Other | Estimated recovery: TBD | Posted Nov 21, 2023 Updated Oct 14, 2026 |
| Phenergan, Injection, 50 mg/1 mL (NDC 0641-6085-25) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
Other | Estimated recovery: TBD | Posted Nov 21, 2023 Updated Oct 14, 2026 |
| Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 39822-5525-3) | XGen Pharmaceuticals DJB, Inc. | Current Available |
— | Posted Nov 21, 2023 Updated Sep 22, 2026 | |
| Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 39822-5550-6) | XGen Pharmaceuticals DJB, Inc. | Current Unvailable |
Demand increase for the drug | Estimated recovery: TBD | Posted Nov 21, 2023 Updated Sep 22, 2026 |