Sodium Bicarbonate Injection shortage
Current 15 presentations · 5 manufacturers · first FDA posting Mar 1, 2017 · last update Oct 15, 2026
Manufacturers: Amphastar Pharmaceuticals, Inc., Exela Pharma Sciences, LLC, Fresenius Kabi USA, LLC, Hospira, Inc., a Pfizer Company, Long Grove Pharmaceuticals LLC
Stated reasons (per FDA): Demand increase for the drug; Other
More info: FDA Drug Shortages Database · ASHP drug shortages list (search there for this drug)
Presentations
| Presentation | Manufacturer | Status | Reason | Notes (FDA) | Dates |
|---|---|---|---|---|---|
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 76329-3352-1) | Amphastar Pharmaceuticals, Inc. | Current Limited Availability |
Demand increase for the drug | Available on allocation | Posted Mar 1, 2017 Updated Oct 5, 2026 |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 51754-5001-5) | Exela Pharma Sciences, LLC | Current Available |
— | Posted Jul 24, 2017 Updated Oct 15, 2026 | |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 51754-5011-4) | Exela Pharma Sciences, LLC | Current Available |
— | Posted Jul 24, 2017 Updated Oct 15, 2026 | |
| Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 51754-5012-4) | Exela Pharma Sciences, LLC | Current Available |
— | Posted Jul 24, 2017 Updated Oct 15, 2026 | |
| Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 63323-083-05) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory. | Posted Jul 24, 2017 Updated Oct 15, 2026 |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 63323-089-50) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted Jul 24, 2017 Updated Oct 15, 2026 |
| Sodium Bicarbonate, Injection, 2.5 mEq/5 mL (4.2%, 0.5 mEq/mL) (NDC 0409-5555-01) | Hospira, Inc., a Pfizer Company | Current Limited Availability |
Other | Limited Supply Available. Next Delivery: May 2027; Estimated Recovery: June 2027; Shortage per Manufacturer: Manufacturing Delay | Posted Mar 1, 2017 Updated Oct 8, 2026 |
| Sodium Bicarbonate, Injection, 2.5 mEq/5 mL (4.2%, 0.5 mEq/mL) (NDC 0409-5555-02) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted Mar 1, 2017 Updated Oct 8, 2026 | |
| Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) (NDC 0409-6625-14) | Hospira, Inc., a Pfizer Company | Current Limited Availability |
Other | Limited Supply Available. Next Delivery: October 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay | Posted Mar 1, 2017 Updated Oct 8, 2026 |
| Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) (NDC 0409-6625-35) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery: January 2027; Estimated Recovery: March 2027; Shortage per Manufacturer: Manufacturing Delay | Posted Mar 1, 2017 Updated Oct 8, 2026 |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 81298-7620-3) | Long Grove Pharmaceuticals LLC | Current Available |
— | Posted Mar 1, 2017 Updated Oct 1, 2026 | |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 0409-4900-14) | Hospira, Inc., a Pfizer Company | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted Nov 7, 2025 Updated Nov 7, 2025 Discontinued Nov 7, 2025 |
| Sodium Bicarbonate, Injection, 75 mg/1 mL (NDC 0409-4916-14) | Hospira, Inc., a Pfizer Company | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted Nov 7, 2025 Updated Nov 7, 2025 Discontinued Nov 7, 2025 |
| Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 0409-5534-14) | Hospira, Inc., a Pfizer Company | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted Nov 7, 2025 Updated Nov 7, 2025 Discontinued Nov 7, 2025 |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 0409-6637-14) | Hospira, Inc., a Pfizer Company | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted Nov 7, 2025 Updated Nov 7, 2025 Discontinued Nov 7, 2025 |